Secondary T cell–T cell synaptic interactions drive the differentiation of protective CD8+ T cells
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چکیده
منابع مشابه
T-bet-mediated differentiation of the activated CD8+ T cell
The T-box transcription factor, T-bet promotes the differentiation of short-lived effector CD8(+) T cells at the expense of central memory cells. How T-bet mediates these effects, and whether they are directly caused by T-bet alone are unknown, because expression of T-bet requires stimulation of the T cell by inflammatory and growth cytokines, which may have T-bet-independent functions involvin...
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ژورنال
عنوان ژورنال: Nature Immunology
سال: 2013
ISSN: 1529-2908,1529-2916
DOI: 10.1038/ni.2547